November 12, 2014
Notes: Giorda, Carlo B
Research Support, Non-U.S. Gov’t
Lancet Diabetes Endocrinol. 2014 Feb;2(2):111-5. doi: 10.1016/S2213-8587(13)70147-5. Epub 2013 Nov 12.
Author Address: Metabolism and Diabetes Unit, ASL TO5, Regione Piemonte, Chieri, Italy. Electronic address: email@example.com.
Epidemiology Unit, ASL TO3, Regione Piemonte, Grugliasco, Italy.
Chaira Medica Association, Chieri, Italy.
Metabolism and Diabetes Unit, ASL TO5, Regione Piemonte, Chieri, Italy.
Epidemiology Unit, ASL TO3, Regione Piemonte, Grugliasco, Italy; Department of Public Health, University of Torino, Torino, Italy.
Reference Type: Journal Article
Record Number: 4669Author: Goransky, J., Alvarez, F. A., Picco, P., Spina, J. C., Santibanes, Md and Mazza, O.
Title: Groove pancreatitis vs groove pancreatic adenocarcinoma. Report of two cases and review of the literature
Journal: Acta Gastroenterol Latinoam
Short Title: Groove pancreatitis vs groove pancreatic adenocarcinoma. Report of two cases and review of the literature
Alternate Journal: Acta gastroenterologica Latinoamericana
ISSN: 0300-9033 (Print)
Accession Number: 24303693
Tomography, X-Ray Computed
Abstract: Groove pancreatitis (GP) is a rare form of segmental chronic pancreatitis affecting the groove area (anatomic space between the head of the pancreas, the duodenum and the common bile duct). Its clinical and radiological presentation may be similar to groove pancreatic adenocarcinoma (GPA). Nevertheless, treatment and prognosis are totally different. We report two cases of both GP and GPA and review the relevant aspects that may help to clarify the differential diagnosis between these two rare entities. The first patient is a 57-year-old man with a history of chronic alcohol consumption who presented with persistent abdominal pain. The CT-scan findings suggested GP. Due to the persistence of symptoms despite medical treatment, a pancreaticoduodenectomy was performed. Pathologic evaluation confirmed the diagnosis of GP. The second patient is a 72-year-old male who presented with cholestasis and weight loss. The tumor marker CA 19-9 was increased The CT-scan findings were consistent with duodenal dystrophy. In order to rule out malignancy a pancreaticoduodenectomy was performed. Pathologic evaluation revealed a pancreatic head adenocarcinoma (T3-N1-M0). GP is a rare entity that should be suspected in patients with a history of heavy alcohol consumption who complain of chronic abdominal pain and weight loss. Patients without a clear diagnosis even after a through imaging work-up, or those in whom symptoms are persistent in spite of medical therapy, should undergo surgical exploration.