November 12, 2014
Notes: Zafar, Arif
Jameel, Jainudeen K A
Int J Surg Case Rep. 2013;4(5):528-30. doi: 10.1016/j.ijscr.2013.01.017. Epub 2013 Feb 8.
Author Address: Department of General & Upper Gastrointestinal Surgery, Dewsbury & District Hospital, The Mid Yorkshire Hospitals NHS Trust, Halifax Road, Dewsbury, West Yorkshire WF13 4HS, United Kingdom. Electronic address: email@example.com.
Reference Type: Journal Article
Record Number: 5156Author: Zhang, D. L., Huang, Y., Yan, L., Phu, A., Ran, X. and Li, S. S.
Title: Thirty-eight cases of acute pancreatitis in pregnancy: a 6-year single center retrospective analysis
Journal: J Huazhong Univ Sci Technolog Med Sci
Short Title: Thirty-eight cases of acute pancreatitis in pregnancy: a 6-year single center retrospective analysis
Alternate Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban
ISSN: 1672-0733 (Print)
Accession Number: 23771661
Abstract: Thirty-eight pregnant inpatients with acute pancreatitis (AP) were retrospectively reviewed from 2006 to 2012 in our hospital. The incidence of pregnancy-associated AP was 2.27 per thousand. Most (78.95%) of the attack occurred in the third trimester. The median of APACHE II score was 6 and severe AP accounted for 31.58% (12 cases). Primary diseases were absent in most cases (57.89%). The most common clinical presentations were abdominal pain (89.47%) and vomiting (68.42%). Pleural effusion and ascites were found only in the third trimester. Elevated white blood cell count, amylase and lipase were commonly found in biochemical examinations. Eleven cases required intensive care in ICU and 21 cases received caesarean section. There were 2 maternal deaths and 12 fetal losses including 4 abortions. It is concluded that AP is a rare entity in pregnancy. The incidence of pancreatitis increases with the gestational age. However, the severity is not necessarily related with the pregnancy trimesters. The diagnosis is based on clinical presentations, laboratory tests and imaging examinations. Although the treatment strategy of a pregnant woman with pancreatitis is similar to the general non-pregnant patient with AP, a multidisciplinary team consisting of gastroenterologist, gastrointestinal surgeon, radiologist, obstetrician, and ICU doctor should be set up.