November 12, 2014
van Erpecum, Karel J
Mulder, Chris J J
Bruno, Marco J
Pancreas. 2013 Jul;42(5):774-80. doi: 10.1097/MPA.0b013e318287d208.
Author Address: Department of Gastroenterology and Hepatology, Raboud University Medical Center Nijmegen, Nijmegen, The Netherlands. firstname.lastname@example.org
Reference Type: Journal Article
Record Number: 5114Author: Vidarsdottir, H., Moller, P. H., Vidarsdottir, H., Thorarinsdottir, H. and Bjornsson, E. S.
Title: Acute pancreatitis: a prospective study on incidence, etiology, and outcome
Journal: Eur J Gastroenterol Hepatol
Short Title: Acute pancreatitis: a prospective study on incidence, etiology, and outcome
Alternate Journal: European journal of gastroenterology & hepatology
ISSN: 1473-5687 (Electronic)
Accession Number: 23839162
Keywords: Acute Disease
Aged, 80 and over
Alcohol Drinking/adverse effects/epidemiology
Pancreatitis, Acute Necrotizing/diagnosis/epidemiology/therapy
Respiratory Distress Syndrome, Adult/diagnosis/epidemiology/therapy
Severity of Illness Index
Abstract: BACKGROUND AND AIMS: Prospective and population-based studies on the incidence of acute pancreatitis (AP) are lacking. Alcohol consumption has increased considerably in Iceland during the last decade. We aimed to determine the incidence, etiology, severity, and complications of AP and compare the results with a previous study on AP in Iceland. METHODS: A prospective population-based study of patients diagnosed with AP at the National University Hospital of Iceland during 1 year (2010-2011). Information on symptoms, etiology, and complications was registered. RESULTS: During the study period, 134 patients were diagnosed with AP, 78 men (58%), median age 57 years (interquartile range 42-71). Overall, 89/104 (86%) patients had their first attack of pancreatitis, yielding a crude incidence of 40/100 000 inhabitants/year. The major etiological groups were as follows: gallstones, 52 cases (42%); alcohol 29, (23%); postendoscopic retrograde cholangio-pancreatography in 12 (9.5%); medications in eight (6.3%); and idiopathic in 15 (12%). Alcohol was more often the cause in men (25 vs. 4, P<0.05) but the incidence of gallstone-induced pancreatitis was similar in men and women (26 vs. 27). Seven patients had severe complications, three had pancreatic necrosis, two had pseudocysts, and one developed renal failure. Another patient developed acute respiratory distress syndrome and was admitted to the ICU. No patient died of AP during the study period. CONCLUSION: The incidence of AP has not increased significantly in Iceland in the last decade. Alcohol-induced pancreatitis has not increased proportionally despite increased alcohol consumption in Iceland. In a population-based setting, the vast majority of AP is of mild severity.