November 12, 2014
Notes: Lima, Patricia Rodrigues
de Melo, Tiago Sousa
Carvalho, Karine Maria Martins Bezerra
de Oliveira, Italo Bonfim
Arruda, Bruno Rodrigues
de Castro Brito, Gerly Anne
Rao, Vietla Satyanarayana
Santos, Flavia Almeida
Research Support, Non-U.S. Gov’t
Life Sci. 2013 Jul 10;92(24-26):1195-201. doi: 10.1016/j.lfs.2013.05.009. Epub 2013 May 20.
Author Address: Post-Graduate Programme in Medical Sciences, Faculty of Medicine, Federal University of Ceara, 60430-140 Fortaleza, Ceara, Brazil.
Reference Type: Journal Article
Record Number: 5240Author: Limwattana, S., Dissaneewate, P., Kritsaneepaiboon, S., Dendumrongsup, T. and Vachvanichsanong, P.
Title: Systemic lupus erythematosus-related pancreatitis in children
Journal: Clin Rheumatol
Short Title: Systemic lupus erythematosus-related pancreatitis in children
Alternate Journal: Clinical rheumatology
ISSN: 1434-9949 (Electronic)
Accession Number: 23673437
Keywords: Abdominal Pain/complications/drug therapy
Adrenal Cortex Hormones/therapeutic use
Anti-Bacterial Agents/therapeutic use
Lupus Erythematosus, Systemic/*complications/physiopathology
Prednisolone/adverse effects/*therapeutic use
Tomography, X-Ray Computed
Abstract: We report on three patients who developed four episodes of acute pancreatitis while their systemic lupus erythematosus was active and being treated with prednisolone. In all three, gastritis was first considered and treated due to abdominal pain, vomiting, and epigastric tenderness, but their symptoms did not improve. Then pancreatic enzymes were measured, which confirmed pancreatitis. Imaging studies showed an enlarged pancreas in one case, a normal pancreas in two cases, and a focal hypodense nonenhancing parenchyma in one case. Corticosteroids were prescribed for both active SLE and SLE-related pancreatitis. Pulse methylprednisolone was prescribed in one episode, increasing oral prednisolone in one episode, and the same dose of prednisolone continued in the other two episodes. All cases recovered without complications. SLE-related pancreatitis should be considered in SLE patients when the SLE is active and a patient develops abdominal pain and vomiting.