November 12, 2014
Record Number: 4649Author: Dominguez-Munoz, J. E.
Title: [Latest advances in chronic pancreatitis]
Journal: Gastroenterol Hepatol
Volume: 36 Suppl 2
Short Title: [Latest advances in chronic pancreatitis]
Alternate Journal: Gastroenterologia y hepatologia
ISSN: 0210-5705 (Print)
Original Publication: Ultimos avances en pancreatitis cronica.
Accession Number: 24160957
Abstract: This article summarizes some of the recent and clinically relevant advances in chronic pancreatitis. These advances mainly concern knowledge of the etiopathogenesis of the disease, the pharmacological treatment of pain, and knowledge of the natural history of autoimmune pancreatitis. New evidence supports the relatively low prevalence of chronic alcoholic pancreatitis, and the role of tobacco in triggering the etiopathogenic mechanisms of chronic pancreatitis is better understood. Some studies have identified certain factors that are associated with having a positive genetic test in adults with chronic idiopathic pancreatitis, which should help to select those patients who should undergo genetic studies. Antioxidant therapy has been shown to be effective in reducing pain secondary to chronic pancreatitis, although the type and optimal dose of antioxidants remains to be elucidated. Finally, the development of exocrine and endocrine pancreatic insufficiency is a very common finding during the long-term follow-up of patients with autoimmune pancreatitis. Smoking also seems to play a role in this type of pancreatitis.
Notes: Dominguez-Munoz, J Enrique
Gastroenterol Hepatol. 2013 Oct;36 Suppl 2:86-9. doi: 10.1016/S0210-5705(13)70058-X.
Author Address: Servicio de Aparato Digestivo, Hospital Clinico Universitario de Santiago, Santiago de Compostela, A Coruna, Espana. Electronic address: firstname.lastname@example.org.