November 12, 2014
Nihon Shokakibyo Gakkai Zasshi. 2013 May;110(5):875-82.
Author Address: Department of Gastroenterology, Japanese Red Cross Nagoya Daiichi Hospital, Japan. firstname.lastname@example.org
Reference Type: Journal Article
Record Number: 5272Author: Issa, Y., van Santvoort, H. C., van Goor, H., Cahen, D. L., Bruno, M. J. and Boermeester, M. A.
Title: Surgical and endoscopic treatment of pain in chronic pancreatitis: a multidisciplinary update
Journal: Dig Surg
Short Title: Surgical and endoscopic treatment of pain in chronic pancreatitis: a multidisciplinary update
Alternate Journal: Digestive surgery
ISSN: 1421-9883 (Electronic)
Accession Number: 23635532
Abstract: Chronic pancreatitis is an inflammatory disease of the pancreas with abdominal pain as the most prominent symptom. Adequate treatment of patients with chronic pancreatitis remains a major challenge, mainly because of the lack of evidence-based treatment protocols. The primary goal of treatment is to achieve long-term pain relief, control of the complications associated with the disease, and to restore the quality of life. Currently, a conservative step-up approach is often used for the treatment of pain; progression to severe and intractable pain is considered necessary before invasive treatment is considered. Recent studies, however, suggest that surgical intervention should not be considered only as last-resort treatment, since it can mitigate disease progression, achieve excellent pain control, and preserve pancreatic function. In this review, we present a state-of-the art overview of endoscopic and surgical treatment options for patients with painful chronic pancreatitis, and elaborate on the timing of surgery.