November 12, 2014
Severity of Illness Index
Abstract: BACKGROUND/AIMS: Predicting the severity of acute pancreatitis is limited to clinical, laboratory and radiological risk factors. Hepcidin levels increase in acute inflammation. We aimed to assess the relationship between hepcidin and C-reactive protein (CRP), white blood cells (WBC) and multi-detector computerized tomography (MDCT) in predicting the severity of pancreatitis. METHODOLOGY: We undertook a prospective review of 59 consecutive patients with acute pancreatitis admitted to our clinic. Biochemical values were measured from blood samples taken within 2 hours of admission and from between 2 and 72 hours related to the time of symptom onset. RESULTS: In predicting severe acute pancreatitis, hepcidin was superior to CRP and WBC (Area Under the Curve (AUC)=0.79, p=0.003; AUC=0.69, p=NS; AUC=0.53, p=NS, respectively). CONCLUSIONS: In this study, hepcidin was found to be superior to CRP in predicting the severity of pancreatitis.
Notes: Arabul, Mahmut
Hepatogastroenterology. 2013 May;60(123):595-600. doi: 10.5754/hge12770.
Author Address: Department of Gastroenterology, Izmir Katip Celebi University, Ataturk Training and Research Hospital, Izmir, Turkey. email@example.com
Reference Type: Journal Article
Record Number: 5296Author: Arakawa, Y., Yoshioka, K., Kamo, H., Kawano, K., Yamaguchi, T., Sumise, Y., Okitsu, N., Ikeyama, S., Morimoto, K., Nakai, Y. and Tashiro, S.
Title: Huge retroperitoneal dedifferentiated liposarcoma presented as acute pancreatitis: report of a case
Journal: J Med Invest
Short Title: Huge retroperitoneal dedifferentiated liposarcoma presented as acute pancreatitis: report of a case