November 12, 2014
Alternate Journal: Nature reviews. Gastroenterology & hepatology
ISSN: 1759-5053 (Electronic)
Accession Number: 23999320
Keywords: Carboxypeptidases A/*genetics
*Genetic Predisposition to Disease
Notes: Wood, Natalie J
Nat Rev Gastroenterol Hepatol. 2013 Oct;10(10):567. doi: 10.1038/nrgastro.2013.172. Epub 2013 Sep 3.
Reference Type: Journal Article
Record Number: 5081Author: Worhunsky, D. J. and Visser, B. C.
Title: Gallstone pancreatitis: why not cholecystectomy?
Journal: JAMA Surg
Short Title: Gallstone pancreatitis: why not cholecystectomy?
Alternate Journal: JAMA surgery
ISSN: 2168-6262 (Electronic)
Accession Number: 23884335
Keywords: *Cholangiopancreatography, Endoscopic Retrograde
Notes: Worhunsky, David J
Visser, Brendan C
JAMA Surg. 2013 Sep;148(9):872. doi: 10.1001/jamasurg.2013.3063.
Author Address: Department of Surgery, Stanford University Medical Center, Stanford, California.
Reference Type: Journal Article
Record Number: 4928Author: Working Group, I. A. P. A. P. A. Acute Pancreatitis Guidelines
Title: IAP/APA evidence-based guidelines for the management of acute pancreatitis
Issue: 4 Suppl 2
Short Title: IAP/APA evidence-based guidelines for the management of acute pancreatitis
Alternate Journal: Pancreatology : official journal of the International Association of Pancreatology
ISSN: 1424-3911 (Electronic)
Accession Number: 24054878
Keywords: Acute Disease
Pancreatitis, Acute Necrotizing/diagnosis/surgery/*therapy
Abstract: BACKGROUND: There have been substantial improvements in the management of acute pancreatitis since the publication of the International Association of Pancreatology (IAP) treatment guidelines in 2002. A collaboration of the IAP and the American Pancreatic Association (APA) was undertaken to revise these guidelines using an evidence-based approach. METHODS: Twelve multidisciplinary review groups performed systematic literature reviews to answer 38 predefined clinical questions. Recommendations were graded using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. The review groups presented their recommendations during the 2012 joint IAP/APA meeting. At this one-day, interactive conference, relevant remarks were voiced and overall agreement on each recommendation was quantified using plenary voting. RESULTS: The 38 recommendations covered 12 topics related to the clinical management of acute pancreatitis: A) diagnosis of acute pancreatitis and etiology, B) prognostication/predicting severity, C) imaging, D) fluid therapy, E) intensive care management, F) preventing infectious complications, G) nutritional support, H) biliary tract management, I) indications for intervention in necrotizing pancreatitis, J) timing of intervention in necrotizing pancreatitis, K) intervention strategies in necrotizing pancreatitis, and L) timing of cholecystectomy. Using the GRADE system, 21 of the 38 (55%) recommendations, were rated as ‘strong’ and plenary voting revealed ‘strong agreement’ for 34 (89%) recommendations. CONCLUSIONS: The 2012 IAP/APA guidelines provide recommendations concerning key aspects of medical and surgical management of acute pancreatitis based on the currently available evidence. These recommendations should serve as a reference standard for current management and guide future clinical research on acute pancreatitis.