November 12, 2014
Notes: Tandan, Manu
Nageshwar Reddy, D
World J Gastroenterol. 2013 Oct 7;19(37):6156-64. doi: 10.3748/wjg.v19.i37.6156.
Author Address: Manu Tandan, D Nageshwar Reddy, Department of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, India.
Reference Type: Journal Article
Record Number: 5068Author: Tandan, M., Reddy, D. N., Talukdar, R., Vinod, K., Santosh, D., Lakhtakia, S., Gupta, R., Ramchandani, M. J., Banerjee, R., Rakesh, K., Varadaraj, G. and Rao, G. V.
Title: Long-term clinical outcomes of extracorporeal shockwave lithotripsy in painful chronic calcific pancreatitis
Journal: Gastrointest Endosc
Short Title: Long-term clinical outcomes of extracorporeal shockwave lithotripsy in painful chronic calcific pancreatitis
Alternate Journal: Gastrointestinal endoscopy
ISSN: 1097-6779 (Electronic)
Accession Number: 23891416
Keywords: Abdominal Pain/etiology/*therapy
Cholangiopancreatography, Endoscopic Retrograde
Quality of Life
Abstract: BACKGROUND: Long-term results of extracorporeal shockwave lithotripsy (ESWL) for large pancreatic duct (PD) stones in patients with idiopathic calcific pancreatitis (CP) are scanty. OBJECTIVE: To evaluate intermediate and long-term results of ESWL in a large cohort of patients with idiopathic CP. DESIGN: Cross-sectional study; retrospective chart review. SETTING: A high-volume, tertiary-care center for endoscopy and GI diseases. PATIENTS: A total of 636 patients with idiopathic CP who underwent ESWL and ERCP were followed-up. Patients were divided into intermediate (24-60 months) and long-term (>60 months) follow-up groups. INTERVENTION: ESWL and ERCP. MAIN OUTCOME MEASUREMENTS: Improvement in pain, analgesic use, hospitalization for pain, recurrence of calculi, need for additional intervention, and quality of life. RESULTS: A total of 636 of 1006 patients who underwent ESWL between 2004 and 2009 were followed for a maximum of 96 months. There were 364 patients in the intermediate follow-up group and 272 in the long-term follow-up group. After ESWL and ERCP, absence of pain was seen in 250 patients (68.7%), mild-to-moderate pain in 94 patients (25.4%), and severe pain in 20 patients (5.5%) of the intermediate group. In the long-term group, 164 patients (60.3%) had no pain, 97 patients (35.7%) had mild or moderate episodes of pain, whereas 11 patients (4.04%) had episodic severe pain. Recurrence of calculi was seen in 51 patients (14.01%) in the intermediate follow-up group and in 62 patients (22.8%) in the long-term group. Quality of life improved in a significant number of patients in both groups. LIMITATIONS: Retrospective study, single center, recall bias, and subjective pain and quality-of-life measurement scale. CONCLUSION: ESWL for large PD calculi offers good results in patients of idiopathic CP on intermediate and long-term follow-up.