November 12, 2014
Notes: Kamisawa, Terumi
Ryu, Ji Kon
Kim, Myung Hwan
Chung, Jae Bock
Gut Liver. 2013 Jul;7(4):394-400. doi: 10.5009/gnl.2013.7.4.394. Epub 2013 Jul 11.
Author Address: Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan.
Reference Type: Journal Article
Record Number: 4975Author: Kang, S. J., Yoon, K. H. and Hwang, J. B.
Title: Epstein-barr virus infection with acute pancreatitis associated with cholestatic hepatitis
Journal: Pediatr Gastroenterol Hepatol Nutr
Short Title: Epstein-barr virus infection with acute pancreatitis associated with cholestatic hepatitis
Alternate Journal: Pediatric gastroenterology, hepatology & nutrition
ISSN: 2234-8646 (Print)
Accession Number: 24010108
Abstract: Infection-induced acute hepatitis complicated with acute pancreatitis is associated with hepatitis A virus, hepatitis B virus or hepatitis E virus. Although rare, Epstein-Barr virus (EBV) infection should be considered also in the differential diagnosis if the patient has acute hepatitis combined with pancreatitis. We report a case of EBV infection with cholestatic hepatitis and pancreatitis with review of literature. An 11-year-old female was admitted due to 1-day history of abdominal pain and vomiting without any clinical symptoms of infectious mononucleosis. Diagnosis of reactivated EBV infection was made by the positive result of viral capsid antigen (VCA) IgM, VCA IgG, Epstein-Barr nuclear antigen and heterophile antibody test. We performed serologic tests and magnetic resonance cholangiopancreatography to exclude other viral or bacterial infection, autoimmune disorder, and structural problems. The patient’s symptoms recovered rapidly and blood chemistry returned to normal with conservative treatment similar to previously reported cases.