November 12, 2014
Notes: Gorges, Rony
J Invasive Cardiol. 2013 Oct;25(10):E203-4.
Author Address: Providence Hospital, GME, 16001 W Mile 9 Road, Southfield, MI 48075 USA. email@example.com.
Reference Type: Journal Article
Record Number: 5088Author: Gou, S., Xiong, J., Wu, H., Zhou, F., Tao, J., Liu, T. and Wang, C.
Title: Five-year cohort study of open pancreatic necrosectomy for necotizing pancreatitis suggests it is a safe and effective operation
Journal: J Gastrointest Surg
Short Title: Five-year cohort study of open pancreatic necrosectomy for necotizing pancreatitis suggests it is a safe and effective operation
Alternate Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
ISSN: 1873-4626 (Electronic)
Accession Number: 23868057
Pancreatitis, Acute Necrotizing/mortality/*surgery
Abstract: INTRODUCTION: Despite advances in the management of necrotizing pancreatitis, open necrosectomy remains an important management option for necrotizing pancreatitis, and patients undergoing necrosectomy suffer significant morbidity and mortality. The aim of this study was to report the outcomes of open necrosectomy from a recent large cohort of patients with necrotizing pancreatitis. METHODS: Data are reported from a cohort of 276 consecutive patients with necrotizing pancreatitis who underwent open surgical debridement. Nutritional status, nutritional methods, bleeding, infection, demarcation of necrotic tissues, and time from onset of disease were scored. Scores >/= 10 were considered as an indication for debridement. RESULTS: One hundred sixty-two (58.7%) and 52 (18.8%) patients underwent minimally invasive peritoneal and retroperitoneal drainage, respectively, before necrosectomy. Median delay from disease onset to debridement was 48 days. Fifty-five patients (19.9%) underwent more than one operation; 352 operations were performed in total. There were 17 deaths (6.2%) postoperatively. CONCLUSION: This study demonstrated the results for open debridement in a recent large cohort of patients. Although minimally invasive necrosectomy has been developed in recent years, open necrosectomy remains an important approach for the debridement of necrotizing pancreatitis effectively and safely.