November 12, 2014
ISSN: 1784-3286 (Print)
Accession Number: 24455804
Keywords: Abdominal Wall
Antineoplastic Combined Chemotherapy Protocols/*adverse effects
Doxorubicin/administration & dosage
Ifosfamide/administration & dosage
Abstract: Drug-induced pancreatitis is rare (1.4-2%). This report describes a 20-year-old female patient who developed acute pancreatitis while being treated for neurosarcoma of abdominal wall with the ifosfamide and doxorubicin regimen. Although it is unusual, it is important to consider chemotherapeutic agents as a possible etiology for acute pancreatitis in patients presenting with gastrointestinal symptoms.
Notes: Ben Kridis, W
Acta Clin Belg. 2013 Jul-Aug;68(4):309-10.
Author Address: Department of Oncology, Habib Bourguiba Hospital, Sfax 3029, Tunisia. firstname.lastname@example.org
Department of Oncology, Habib Bourguiba Hospital, Sfax 3029, Tunisia.
Reference Type: Journal Article
Record Number: 4616Author: Berglund, L., Brunzell, J. D., Goldberg, A. C., Goldberg, I. J. and Stalenhoef, A.
Title: Treatment options for hypertriglyceridemia: from risk reduction to pancreatitis
Journal: Best Pract Res Clin Endocrinol Metab
Short Title: Treatment options for hypertriglyceridemia: from risk reduction to pancreatitis
Alternate Journal: Best practice & research. Clinical endocrinology & metabolism
ISSN: 1878-1594 (Electronic)
Accession Number: 24840268
Abstract: While there has been considerable focus on the role and treatment of LDL cholesterol levels, a definitive role of triglycerides in the management of cardiovascular disease has been uncertain. Notably, with increasing triglyceride levels, there is a parallel increase in cholesterol levels carried by triglyceride-rich lipoproteins, which has prompted interest in the use of non-HDL cholesterol levels as a tool guiding interventions. Recent studies have provided evidence for an independent role of triglyceride levels as a cardiovascular risk factor, and recently, an Endocrine Society guideline was published for treatment of hypertriglyceridemia. In contrast to the relative uncertainty regarding triglycerides and cardiovascular disease, a role of very high triglyceride levels as a risk factor for pancreatitis has been well known. The present paper summarizes the underlying evidence for a risk role for triglyceride levels in cardiovascular disease and pancreatitis, current treatment recommendations and areas of future research.