Pancreatitis

Notes: Uvelin, Arsen

Hajdukovic, Danica

Vrsajkov, Vladimir

Kolak, Radmila

Lazukic, Aleksandra

Vickovic, Sanja

Gojkovic, Zoran

eng

Case Reports

Croatia

2014/04/05 06:00

Acta Clin Croat. 2013 Dec;52(4):515-22.

URL: http://www.ncbi.nlm.nih.gov/pubmed/24697004

 

 

Reference Type:  Journal Article

Record Number: 4809Author: van Baal, M. C., Bollen, T. L., Bakker, O. J., van Goor, H., Boermeester, M. A., Dejong, C. H., Gooszen, H. G., van der Harst, E., van Eijck, C. H., van Santvoort, H. C., Besselink, M. G. and Dutch Pancreatitis Study, Group

Year: 2014

Title: The role of routine fine-needle aspiration in the diagnosis of infected necrotizing pancreatitis

Journal: Surgery

Volume: 155

Issue: 3

Pages: 442-8

Date: Mar

Short Title: The role of routine fine-needle aspiration in the diagnosis of infected necrotizing pancreatitis

Alternate Journal: Surgery

ISSN: 1532-7361 (Electronic)

0039-6060 (Linking)

DOI: 10.1016/j.surg.2013.10.001

Accession Number: 24287142

Keywords: Adult

Aged

Biopsy, Fine-Needle

Databases, Factual

Drainage

Female

Humans

Male

Middle Aged

Pancreas/microbiology/*pathology/surgery

Pancreatitis, Acute Necrotizing/diagnosis/microbiology/*pathology/surgery

Preoperative Care/methods

Retrospective Studies

Tomography, X-Ray Computed

Treatment Outcome

Abstract: BACKGROUND: Diagnosing infected necrotizing pancreatitis (INP) may be challenging. The aim of this study was to determine the added value of routine fine-needle aspiration (FNA) in addition to clinical and imaging signs of infection in patients who underwent intervention for suspected INP. METHODS: We conducted a post hoc analysis of 208 consecutive patients from a prospective, multicenter database who underwent intervention because of suspected INP. In retrospect, 3 groups were constructed based on the patients preoperative characteristics: Clinical, imaging, and FNA. Patients in the clinical group had clinical signs of infection but no gas on preoperative computed tomography (CT) and no FNA performed before intervention. Patients in the imaging group had gas bubbles on the preoperative CT but no was FNA performed, whereas patients in the FNA group had a positive FNA before intervention. The reference standard for infection was the culture taken during the first intervention (either catheter drainage or necrosectomy). RESULTS: The initial intervention for INP was performed a median of 27 days (interquartile range, 20-39) after admission without difference between the 3 groups (P = .15). Infection was confirmed in 80% of 92 patients of the clinical group, in 94% of 88 patients of the imaging group, and in 86% of 28 patients of the FNA group (P = .07). Mortality was 19% and was not different between groups (P = .39). CONCLUSION: INP can generally be diagnosed based on clinical or imaging signs of infection. FNA may be useful in patients with unclear clinical signs and no imaging signs of INP.

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