Dermatology 2013

Notes: McCleskey, Patrick E

eng

Comparative Study

2013/02/19 06:00

J Am Acad Dermatol. 2013 Aug;69(2):273-9. doi: 10.1016/j.jaad.2012.12.955. Epub 2013 Feb 14.

URL: http://www.ncbi.nlm.nih.gov/pubmed/23415684

Author Address: Uniformed Services University of the Health Sciences, Bethesda, Maryland, and Department of Dermatology, David Grant Medical Center, Travis Air Force Base, California, USA. Patrick.mccleskey@me.com

 

 

Reference Type:  Journal Article

Record Number: 4498Author: McIsaac, M. A., Cook, R. J. and Poulin-Costello, M.

Year: 2013

Title: Incomplete data in randomized dermatology trials: consequences and statistical methodology

Journal: Dermatology

Volume: 226

Issue: 1

Pages: 19-27

Short Title: Incomplete data in randomized dermatology trials: consequences and statistical methodology

Alternate Journal: Dermatology

ISSN: 1421-9832 (Electronic)

1018-8665 (Linking)

DOI: 10.1159/000346247

Accession Number: 23446106

Keywords: Data Collection/*statistics & numerical data

Dermatitis/*drug therapy

Dermatologic Agents/*therapeutic use

Humans

Patient Compliance/*statistics & numerical data

Randomized Controlled Trials as Topic/*standards

*Statistics as Topic

Abstract: Randomized clinical trials can provide the highest level of evidence regarding the effectiveness of therapeutic interventions. When individuals in trials do not complete the planned treatment period it is often not possible to observe the desired outcomes, which results in incomplete data. Here we review various mechanisms which can lead to incomplete data, discuss the impact of these mechanisms, and present strategies for dealing with incomplete data. We discuss these issues in the context of clinical trials in dermatology and provide practical recommendations for planning and drawing conclusions from studies which could involve incomplete data.

Notes: McIsaac, Michael A

Cook, Richard J

Poulin-Costello, Melanie

eng

Switzerland

Basel, Switzerland

2013/03/01 06:00

Dermatology. 2013;226(1):19-27. doi: 10.1159/000346247. Epub 2013 Feb 23.

Pages: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295