November 8, 2014
Notes: Liakou, Aikaterini I
Theodorakis, Michael J
Melnik, Bodo C
Zouboulis, Christos C
J Drugs Dermatol. 2013 Oct;12(10):1104-9.
Reference Type: Journal Article
Record Number: 4356Author: Lindberg, M., Bingefors, K., Meding, B. and Berg, M.
Title: Hand eczema and health-related quality of life; a comparison of EQ-5D and the Dermatology Life Quality Index (DLQI) in relation to the Hand Eczema Extent Score (HEES)
Journal: Contact Dermatitis
Short Title: Hand eczema and health-related quality of life; a comparison of EQ-5D and the Dermatology Life Quality Index (DLQI) in relation to the Hand Eczema Extent Score (HEES)
Alternate Journal: Contact dermatitis
ISSN: 1600-0536 (Electronic)
Accession Number: 23948032
Aged, 80 and over
*Quality of Life
Severity of Illness Index
Abstract: BACKGROUND: Health-related quality of life (HRQoL) is associated with the extent and severity of hand eczema. We still lack a consensus about which HRQoL instrument to use as the standard, and how to measure the extent and severity of hand eczema. OBJECTIVES: To compare the Dermatology Life Quality Index (DLQI) with EQ-5D (a standardized instrument for use as a measure of health outcome), and to evaluate how the Hand Eczema Extent Score (HEES) relates to these instruments. METHODS: Ninety-three patients (61 females) were included. The HEES was recorded by a dermatologist, and the DLQI and EQ-5D by the patients. The results were analysed with factor analysis and non-parametric statistics. RESULTS: The DLQI and EQ-5D showed decreased HRQoL. Using factor analysis, we could not establish an association between the DLQI and EQ-5D. There were, however, correlations between the DLQI and the HEES (0.31), the EQindex and the HEES (-0.32), the DLQI and the EQVAS (-0.62), and the DLQI and the EQindex (-0.67) (the EQVAS and the EQindex are calculated from EQ-5D). CONCLUSIONS: We could not link factors in the DLQI to EQ-5D, which has previously been done for SF-36 (Short Form 36). On the basis of this, we cannot recommend EQ-5D over SF-36 for hand eczema studies. The DLQI correlates with the EQVAS and the EQindex, and can probably be used as an approximation for EQ-5D. Our findings with the HEES are interesting, as it can be used by patients.