Dermatology 2013

Notes: Gupta, Madhulika A

Gupta, Aditya K

eng

2012/12/19 06:00

Clin Dermatol. 2013 Jan-Feb;31(1):57-61. doi: 10.1016/j.clindermatol.2011.11.007.

URL: http://www.ncbi.nlm.nih.gov/pubmed/23245974

Author Address: Department of Psychiatry, Schulich School of Medicine and Dentistry, University of Western Ontario, 585 Springbank Drive, Suite 101, London, Ontario, N6J 1H3, Canada. magupta@uwo.ca

 

 

Reference Type:  Journal Article

Record Number: 4249Author: Gupta, M. A., Gupta, A. K. and Fink, N. H.

Year: 2013

Title: Polypharmacy in dermatology: analysis of a nationally representative sample of 46,273 dermatology patient visits in the United States from 1995 to 2009

Journal: Skinmed

Volume: 11

Issue: 5

Pages: 273-80

Date: Sep-Oct

Short Title: Polypharmacy in dermatology: analysis of a nationally representative sample of 46,273 dermatology patient visits in the United States from 1995 to 2009

Alternate Journal: Skinmed

ISSN: 1540-9740 (Print)

1540-9740 (Linking)

Accession Number: 24340466

Keywords: Adolescent

Adult

Age Distribution

Aged

Child

Child, Preschool

Dermatologic Agents/administration & dosage/*therapeutic use

Dermatology/*statistics & numerical data/trends

Female

Health Care Surveys

Humans

Infant

Male

Middle Aged

*Polypharmacy

Skin Diseases/*drug therapy/physiopathology/psychology

United States

Young Adult

Abstract: There are no large-scale studies ofpolypharmacy (PP) in dermatology. The authors examined trends in PP (simultaneous use of > or = 4 medications in our study) and associated clinical factors among a nationally representative sample of 46,273 (weighted count +/- standard error [SE]: 617,970,596 +/- 25,187,959) dermatology-related (International Classification of Diseases, Ninth Revision, Clinical Modification codes 680-709) patient visits from 1995 to 2009. Data from the National Ambulatory Medical Care Survey and the National Hospital Ambulatory Care Survey were examined. The overall frequency (+/- SE) of PP was 8.9% +/- 0.4%. There was almost a doubling in the frequency of PP in dermatology from 1995 to 2009 (odds ratio [OR], 2.02; 95% confidence interval [CI], 1.67-2.44, after controlling for comorbidities and sex). This increase was noted among patients with > 1 diagnoses, and all age groups including the younger than 25 age category (PP frequency +/- SE, 7.4% +/- 0.4%; OR, 1.45; 95% CI, 1.12-1.88), and not just among patients in the geriatric age range with multiple complex dermatologic problems. Some of the most frequent conditions in the PP group included acne, psoriasis, atopic dermatitis, and infections of the skin and subcutaneous tissue, conditions that are known to be affected by psychodermatologic factors. PP among these patients may in part be an indication of their complex presentation caused by psychosocial vs dermatopathologic factors.

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