Dermatology 2013

Skin Neoplasms/*diagnosis/*etiology

Tars/*toxicity

Ultraviolet Rays/*adverse effects

Notes: Dickel, Heinrich

Altmeyer, Peter

eng

Case Reports

Letter

Germany

2013/04/12 06:00

J Dtsch Dermatol Ges. 2013 Jun;11(6):553-5. doi: 10.1111/ddg.12056. Epub 2013 Apr 11.

URL: http://www.ncbi.nlm.nih.gov/pubmed/23574986

 

 

Reference Type:  Journal Article

Record Number: 4460Author: Dickey, B. Z., Holland, K. E., Drolet, B. A., Galbraith, S. S., Lyon, V. B., Siegel, D. H. and Chiu, Y. E.

Year: 2013

Title: Demographic and clinical characteristics of cutaneous lupus erythematosus at a paediatric dermatology referral centre

Journal: Br J Dermatol

Volume: 169

Issue: 2

Pages: 428-33

Date: Aug

Short Title: Demographic and clinical characteristics of cutaneous lupus erythematosus at a paediatric dermatology referral centre

Alternate Journal: The British journal of dermatology

ISSN: 1365-2133 (Electronic)

0007-0963 (Linking)

DOI: 10.1111/bjd.12383

Accession Number: 23601021

Keywords: Acute Disease

Adolescent

Age of Onset

Child

Child, Preschool

Chronic Disease

Female

Humans

Infant

Infant, Newborn

Lupus Erythematosus, Cutaneous/*epidemiology/ethnology/pathology

Male

Retrospective Studies

Sex Distribution

Wisconsin/epidemiology

Abstract: BACKGROUND: Paediatric cutaneous lupus erythematosus (CLE) is uncommon and inadequately described in the literature. Similar to adults, children with CLE develop LE-specific and/or LE-nonspecific skin findings. Similarities and differences in demographics and clinical course between paediatric and adult CLE have not been sufficiently described. OBJECTIVES: To detail the demographic and clinical features of paediatric CLE and compare these findings with those reported in the adult literature. METHODS: A retrospective chart review was performed of 53 children seen in a paediatric dermatology clinic with cutaneous manifestations of LE. RESULTS: Patients presented with all five major subtypes of CLE, with some notable differences from adult CLE and previously published reports of paediatric CLE. Progression from discoid LE to systemic LE (SLE) did not occur in our cohort. Patients with subacute CLE were more likely than adults to have lesions below the waist as well as concomitant SLE. Sex distribution for CLE in our study was equal prior to puberty and female predominant in post-pubertal patients. CONCLUSIONS: Children with CLE have variable clinical presentations and progression to SLE that may be different from adult disease. Specifically, children with acute and subacute CLE may be more likely than adults to have systemic disease; therefore, patients with these subtypes should be monitored closely for evidence of SLE. Study limitations included small patient numbers that may limit the ability to generalize these data and relatively short follow-up intervals.

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