November 8, 2014
Notes: Czaika, Viktor
Schmalreck, Arno F
Int J Microbiol. 2013;2013:703905. doi: 10.1155/2013/703905. Epub 2013 Dec 11.
Author Address: Klinik fur Dermatologie, Venerologie und Allergologie, Campus Benjamin Franklin, Charite-Universitatsmedizin Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.
Laboratorium fur medizinische Mikrobiologie, Strasse des Friedens 8, 04579 Molbis, Germany.
BDH-Klinik Greifswald GmbH, Karl-Liebknecht-Ring 26a, 17491 Greifswald, Germany.
Institute of Medical Microbiology, Domagkstrasse 10, 48149 Munster, Germany.
MBS-Microbiology, P.O. Box 101247, 80086 Munich, Germany.
Reference Type: Journal Article
Record Number: 4556Author: Darlenski, R. and Fluhr, J. W.
Title: Photodynamic therapy in dermatology: past, present, and future
Journal: J Biomed Opt
Short Title: Photodynamic therapy in dermatology: past, present, and future
Alternate Journal: Journal of biomedical optics
ISSN: 1560-2281 (Electronic)
Accession Number: 23149885
Abstract: Photodynamic therapy (PDT) is a noninvasive therapeutic method first introduced in the field of dermatology. It is mainly used for the treatment of precancerous and superficial malignant skin tumors. Today PDT finds new applications not only for nononcologic dermatoses but also in the field of other medical specialties such as otorhinolaryngology, ophthalmology, neurology, gastroenterology, and urology. We are witnessing a broadening of the spectrum of skin diseases that are treated by PDT. Since its introduction, PDT protocol has evolved significantly in terms of increasing method efficacy and patient safety. In this era of evidence-based medicine, it is expected that much effort will be put into creating a worldwide accepted consensus on PDT. A review on the current knowledge of PDT is given, and the historical basis of the method’s evolution since its introduction in the 1900s is presented. At the end, future challenges of PDT are focused on discussing gaps that exist for research in the field.