November 8, 2014
Notes: Barbosa, Naiara S
Kalaaji, Amer N
Complement Ther Clin Pract. 2014 Feb;20(1):11-5. doi: 10.1016/j.ctcp.2013.11.003. Epub 2013 Nov 20.
Author Address: Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55901, USA. Electronic address: firstname.lastname@example.org.
Department of Dermatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55901, USA. Electronic address: email@example.com.
Reference Type: Journal Article
Record Number: 4280Author: Basset-Seguin, N.
Title: [PDT panoramic view. Principle, photosensitizers, light sources and validated indications in dermatology]
Journal: Ann Dermatol Venereol
Volume: 140 Suppl 2
Short Title: [PDT panoramic view. Principle, photosensitizers, light sources and validated indications in dermatology]
Alternate Journal: Annales de dermatologie et de venereologie
ISSN: 0151-9638 (Print)
Original Publication: Revue Panoramique de la PDT. Principe, photo-sensibilisateurs, sources de lumieres et indications validees en dermatologie.
Accession Number: 24199714
Keywords: Aminolevulinic Acid/analogs & derivatives/therapeutic use
Bowen’s Disease/drug therapy
Carcinoma, Basal Cell/drug therapy
Clinical Trials as Topic
Keratosis, Actinic/drug therapy
Photosensitizing Agents/therapeutic use
Practice Guidelines as Topic
Precancerous Conditions/drug therapy
Skin Diseases/*drug therapy
Skin Neoplasms/drug therapy
Abstract: INTRODUCTION: Photodynamic therapy (PDT) combines the use of a topical sensitizer and its excitation with a light of appropriate wavelength. Its use in dermatooncology has been possible in France in 2006 when the methyl ester ALA or Metvixia(R) got approved. OBJECTIVE: To provide a panoramic view of validated indications of PDT in oncodermatology. METHOD: This work is based on the review of the literature as well as available guidelines or recommendation on PDT in dermatology. RESULTS: Standardized protocols and results of the main clinical trials are given for the three major indications in dermatology: actinic keratosis, basal cell carcinoma and Bowen disease. CONCLUSION: PDT has its role to play in the treatment of multiple superficial carcinomas and cutaneous precancerous lesions and its main advantage resides in its optimal healing.