Cardiology 2013

Notes: Alexander, Walter

eng

2013/08/16 06:00

P T. 2013 May;38(5):288-92.

URL: http://www.ncbi.nlm.nih.gov/pubmed/23946622

Author Address: The author is a freelance medical writer living in New York City.

 

 

Reference Type:  Journal Article

Record Number: 406Author: Alfonso, F., Ambrosio, G., Ector, H., Goncalves, L., Pinto, F., Timmis, A., Vardas, P. and Editors’ Network European Society of Cardiology Task, Force

Year: 2013

Title: National Society Cardiovascular Journals and the New European Society of Cardiology search engine

Journal: Eur Heart J

Volume: 34

Issue: 41

Pages: 3161-3

Date: Nov

Short Title: National Society Cardiovascular Journals and the New European Society of Cardiology search engine

Alternate Journal: European heart journal

ISSN: 1522-9645 (Electronic)

0195-668X (Linking)

Accession Number: 24344396

Notes: Alfonso, Fernando

Ambrosio, Giuseppe

Ector, Hugo

Goncalves, Lino

Pinto, Fausto

Timmis, Adam

Vardas, Panos

eng

England

2013/12/18 06:00

Eur Heart J. 2013 Nov;34(41):3161-3.

URL: http://www.ncbi.nlm.nih.gov/pubmed/24344396

 

 

Reference Type:  Journal Article

Record Number: 463Author: Allon, M.

Year: 2013

Title: Evidence-based cardiology in hemodialysis patients

Journal: J Am Soc Nephrol

Volume: 24

Issue: 12

Pages: 1934-43

Date: Dec

Short Title: Evidence-based cardiology in hemodialysis patients

Alternate Journal: Journal of the American Society of Nephrology : JASN

ISSN: 1533-3450 (Electronic)

1046-6673 (Linking)

DOI: 10.1681/ASN.2013060632

PMCID: 3839557

Accession Number: 24136920

Keywords: Cardiology/*methods

Cardiovascular Diseases/mortality/*therapy

Evidence-Based Medicine/*methods

Humans

Kidney Failure, Chronic/mortality/*therapy

*Renal Dialysis/mortality

Abstract: Cardiac events are the major cause of death in hemodialysis patients. Because of the paucity of randomized clinical trials (RCTs) in hemodialysis patients, most cardiovascular therapies in this population are based on observational studies or results extrapolated from studies that excluded hemodialysis patients. However, associations discovered in observational studies do not prove causality, and these studies often report surrogate outcomes rather than clinical end points. Furthermore, interventions that show effectiveness in the general population may have drastically different outcomes and side effect profiles in hemodialysis patients. This review discusses the results of RCTs undertaken recently to evaluate cardiovascular therapies in hemodialysis patients and emphasizes clinically relevant outcomes. Although some interventions have produced similar outcomes in hemodialysis patients and the general population, others have not, suggesting that the management of cardiovascular disease in hemodialysis patients may require strategies that differ from the best practice guidelines applied to general population.

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